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Clinical Research Trials
Participation in research and clinical investigation is an important commitment of Hoag Neurosciences Center in its mission to provide patients access to leading-edge management and treatment for neurological disorders.
Research Programs
Hoag’s sub-specialized team of neuroscientists are actively involved in research to discover new therapies, drugs and other medical advancements to better the lives of patients suffering from neurological conditions.
For information, please call the neuroscience clinical trials nursing staff at 949/764-8190.
Clinical Trials
Hoag Neurosciences Center is currently accepting patients to participate in a number of clinical research trials. Please contact Laura Whitaker, RN at 949/764-8190 or email laura.whitaker@hoaghospital.org to learn more about each protocol and whether you may qualify. Your participation in any trial is entirely voluntary. You may decide to withdraw at any time without losing the benefits of your standard medical care.
Acute Ischemic Stroke
David Brown, MD Principal Investigator
Two trials are currently enrolling for the indication of Acute Ischemic Stroke. One study is designed for those who present to the hospital 3-6 hours after onset of stroke symptoms, the other trial can treat patients 24-48 hours after stroke. All study related doctor visits, study medication, labwork, CT scans and evaluations are at no cost to those who qualify.
Peritumoral Brain Edema
Christopher Duma, MD Principal Investigator
If you have edema (swelling) associated with a brain tumor, you may qualify for this trial. Brain tumors can either be primary or malignant. This study is investigating a non-steroidal medication to possibly replace Decadron, the gold standard in treating brain edema. Treatment lasts for 28 days with a long term extension trial. Participants receive 4 MRIs over a 28 day period, which are at no charge.
Brain and Spine Imaging (MRI)
Michael Brant-Zawadzki, MD Principal Investigator
An investigational contrast agent is being evaluated for approval here in the US for MRI of either the brain or spine. Potential participants must be referred from their doctor for this type of imaging, for any indication. Two MRIs are performed (minimum 1 day apart, maximum 2 weeks apart) to compare the investigational agent to an already FDA approved agent. All MRIs, lab tests, physical exams are at no charge and there is compensation for time and travel.
Acute Repetitive Seizures
Richard Kim, MD Principal Investigator
An alternative to Diastat, this study is evaluating the safety and efficacy of an investigational medication for Acute Repetitive Seizures for patients 2 years old and up. Potential participants must have experienced ARS at least once in the last 6 months, with no status epilepticus in the last year. Compensation is available for time and travel, caregivers are trained on how to administer medication at home.
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